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  • Title: [Pharmacokinetic research on theophylline].
    Author: Tsoĭ AN, Gneushev ET, Bogovskiĭ BP, Kaz'mina EM, Abrosimov AG.
    Journal: Farmakol Toksikol; 1987; 50(1):89-91. PubMed ID: 3556561.
    Abstract:
    Blood serum theophylline concentrations were studied in 6 volunteers and 8 patients with bronchospastic syndrome by using an enzyme immunological assay with a commercial kit "Fedesim" (USA) at intravenous and oral administration of euphylline in a dose of 5 mg/kg. The maximal concentration at intravenous injection of euphylline was reached in volunteers in 15 minutes, at oral administration--in 90 minutes, and in patients--somewhat later.
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