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  • Title: Iris-ciliary complex inhibits protein synthesis by organ cultured mammalian ocular lens cells.
    Author: Bagchi M, Dave AA, Singh AK, Caporale MJ.
    Journal: Invest Ophthalmol Vis Sci; 1987 Apr; 28(4):759-62. PubMed ID: 3557881.
    Abstract:
    Freshly isolated rabbit ocular lenses with or without adhering iris-ciliary complex were organ cultured. It was found that lenses with iris-ciliary complex showed decreased protein synthetic ability. Vimentin, a cytoskeletal protein and MP-26, a membrane associated protein, were used as markers for protein synthetic activity. Removal of the iris-ciliary complex at least partially restores the protein synthetic capability of the lens. The ocular lenses cultured with iris-ciliary complex for 48 hr showed marked equatorial opacities.
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