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  • Title: [Fundamental studies on thyroid stimulating hormone immunoradiometric assay kit (TSH RIABEAD II)].
    Author: Muraki H, Tsutsui K, Sato K, Toyama O, Nakazawa M, Niizuma S.
    Journal: Radioisotopes; 1987 Jan; 36(1):24-7. PubMed ID: 3562907.
    Abstract:
    We have reported fundamental studies on the TSH immunoradiometric assay, using TSH RIABEAD II kit (Dainabot). The sensitivity of the assay was 0.03 mu IU/ml and its C.V. was 27.2%. Intra- and inter-assay C.V. were less than 5%. Dilution test and recovery test were good. Serum TSH level was 0.3-4.0 mu IU/ml in normal subjects, less than 0.03 mu IU/ml in untreated Graves' disease and subacute thyroiditis. Therefore, it was found that the clear difference exist in serum TSH levels between normal subjects and patients with untreated Graves' disease. There was a well correlation on the serum TSH levels between this method and TSH radioimmunoassay kit (Amerlex TSH, r = 0.983). Especially, the measurement of serum TSH levels, using immunoradiometric assay kit, was useful for the diagnosis of patients with Graves' disease.
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