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  • Title: [Horton's disease and rhizomelic pseudopolyarthritis. Developmental data apropos of 95 cases].
    Author: Piton JL, Zagala A, Rebuffet JL, Reynes O, Reynes JF, Souteyrand P, Phelip X.
    Journal: Rev Rhum Mal Osteoartic; 1987 Jan; 54(1):7-13. PubMed ID: 3563372.
    Abstract:
    The many common factors linking rhizomelic pseudopolyarthritis and Horton's disease prompt to compare their respective evolutions and the long-term results of their treatments. The comparative study of 28 patients with temporal Horton's arteritis, proven histologically, and 28 rhizomelic pseudopolyarthritis without arteritis on biopsy, in a total population of 95 patients, confirms the similarity of their clinical and biological signs and show a closely related evolution in the three groups. The evolution leads to a cure approximately 16.4 +/- 14 months in 41 p. cent of the cases. 34 p. cent of the patients are at an advanced stage with a mean follow-up of 37 months and relapses during the weaning period were frequent. 25 p. cent of the patients died. Most deaths occur in the first month of the disease, and occur readily in patients who have received a short treatment with steroids discontinued because of a iatrogenic accident. Cerebral vascular accidents and coronary accidents, arterial hypertension and iatrogenic gastro-intestinal ulcerations are the most frequent complications.
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