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  • Title: Nanomaterial based PVA nanocomposite hydrogels for biomedical sensing: Advances toward designing the ideal flexible/wearable nanoprobes.
    Author: Karimzadeh Z, Mahmoudpour M, Rahimpour E, Jouyban A.
    Journal: Adv Colloid Interface Sci; 2022 Jul; 305():102705. PubMed ID: 35640315.
    Abstract:
    In today's world, the progress of wearable tools has gained increasing momentum. Notably, the demand for stretchable strain sensors has considerably increased owing to various potential and emerging applications like human motion monitoring, soft robotics, prosthetics, and electronic skin. Hydrogels possess excellent biocompatibility, flexibility, and stretchability that render them ideal candidates for flexible/wearable substrates. Among them, enormous efforts were focused on the progress of polyvinyl alcohol (PVA) hydrogels to realize multifunctional wearable sensing through using additives/nanofillers/functional groups to modify the hydrogel network. Herein, this review offers an up-to-date and comprehensive summary of the research progress of PVA hydrogel-based wearable sensors in view of their properties, strain sensory efficiency, and potential applications, followed by specifically highlighting their probes using metallic/non-metallic, liquid metal (LM), 2D materials, bio-nanomaterials, and polymer nanofillers. Indeed, flexible electrodes and strain/pressure sensing performance of designed PVA hydrogels for their effective sensing are described. The representative cases are carefully selected and discussed regarding the construction, merits and demerits, respectively. Finally, the necessity and requirements for future advances of conductive and stretchable hydrogels engaged in the wearable strain sensors are also presented, followed by opportunities and challenges.
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