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  • Title: [Dynamics of the echocardiographic indices of myocardial contractile function in chronic ischemic heart disease under treatment with blockaders of the cardiac beta-adrenergic receptors].
    Author: Komarov FI, Ol'binskaia LI, Bragina GI.
    Journal: Kardiologiia; 1979 Apr; 19(4):26-30. PubMed ID: 35643.
    Abstract:
    The article discusses the results of dynamic echocardiographic examination of 46 patients with chronic ischemic heart disease before and after 15-day treatment with agents capable of blocking beta-receptors: propranolol (anaprilin), pindolol (visken), talinolol (cordan) which were prescribed in mean therapeutical doses. It is shown that agents blocking beta-adrenergic receptors lead to regular decrease in the indices of myocardial contractility. The character of changes in the volumetric characteristics of the left ventricle depends on the initial levels of arterial pressure and the degree of its dynamics during treatment with beta-adrenergic blocking agents. In patients with chronic ischemic heart disease developing against the background of hypertensive disease the dynamics of changes in the volumetric indices depends on the degree of arterial pressure reduction.
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