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  • Title: Prebiotics-A Primeval Measure to Combat Dental Caries: A Short-term Clinical Study.
    Author: Konde S, Ravindran S, Agarwal M, Peethambar P.
    Journal: Int J Clin Pediatr Dent; 2022; 15(Suppl 2):S234-S238. PubMed ID: 35645516.
    Abstract:
    BACKGROUND: Prevention of dental caries is paramount in reducing the global burden of the disease. The consumption of probiotics as a prophylactic and therapeutic agent for dental caries, has certain limitations. Prebiotics are nondigestible food ingredients, that enhance the growth and activity of probiotic microorganism, thereby help in the establishment of a healthy oral environment. AIM: The aim of this study was to evaluate and compare the effect of prebiotics, probiotics, and synbiotics on the salivary Streptococcus mutans (S. mutans) counts and salivary IgA concentrations. METHODOLOGY: Children of age-group 6-9 years with DMFT score of 5 and above were divided into three groups of 10 each: Group 1 (prebiotics), Group 2 (probiotics), and Group 3 (synbiotics). The functional food therapy was done for a period of 1 month twice daily. The S. mutans count and IgA concentrations were assessed pre- and postintervention. The obtained results were subjected to statistical analysis. RESULTS: A statistically significant reduction of S. mutans was seen in all three groups after 1 month. However, no statistically significant difference was noted between the groups. CONCLUSION: Prebitoics can serve as an unfortified and natural means of combating dental caries. HOW TO CITE THIS ARTICLE: Konde S, Ravindran S, Agarwal M, et al. Prebiotics-A Primeval Measure to Combat Dental Caries: A Short-term Clinical Study. Int J Clin Pediatr Dent 2022;15(S-2):S234-S238.
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