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  • Title: Single Breath Counting for Diagnosis and Prediction of Severity of Acute Asthma Exacerbation in Children.
    Author: Sharma D, Saini AK, Jha DK, Tyagi A, Bisht SS.
    Journal: Indian J Pediatr; 2023 Aug; 90(8):776-780. PubMed ID: 35648308.
    Abstract:
    OBJECTIVES: To find correlation between single breath counting (SBC) and spirometry in acute exacerbation of asthma in children. METHODS: A cross-sectional observational study including all children aged 6-12 y age, who presented in outpatient department or emergency room with acute exacerbation of asthma, not fitting in exclusion criteria were enrolled. SBC and spirometry parameters were obtained before treatment and 1 h after initiating treatment (GINA 2017 Guidelines). RESULTS: Significant correlation was observed in SBC and FVC (r = 0.349), FEV1 (r = 0.439), FEF25-75 (r = 0.424), and PEF (r = 0.593). Cutoff value of SBC of 23 was found to be suggestive of severe/life-threatening asthma with sensitivity of 83.3% and specificity of 84.4%. No significant association was found between percent change in SBC and spirometry parameters in response to treatment. CONCLUSIONS: SBC can be used to predict PEF, FEV1, FVC, and FEF25-75 of a patient aged between 6 and 12 y during acute asthma exacerbation. The observed cutoff value of 23 of SBC score has a good sensitivity and specificity to identify life-threatening/severe exacerbation. SBC score significantly increases in response to therapy.
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