These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Uncoupling of oxidative leak formation from lipid peroxidation in the human erythrocyte membrane by antioxidants and desferrioxamine.
    Author: Deuticke B, Lütkemeier P, Sistemich M.
    Journal: Biochim Biophys Acta; 1987 May 12; 899(1):125-8. PubMed ID: 3567189.
    Abstract:
    Human erythrocytes, briefly exposed to t-butylhydroperoxide and then incubated further in the absence of exogenous oxidant, undergo lipid peroxidation and formation of aqueous membrane leaks. Leak formation can be suppressed by various types of antioxidants and by desferrioxamine at concentrations at which lipid peroxidation still proceeds almost unaltered. This uncoupling of the two manifestations of an oxidative membrane damage indicates that loss of the barrier properties is not an obligatory consequence of the presence of peroxidized lipids in biological membranes.
    [Abstract] [Full Text] [Related] [New Search]