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  • Title: Gender differences in cardiovascular and metabolic responses to cold and exercise.
    Author: Stevens GH, Graham TE, Wilson BA.
    Journal: Can J Physiol Pharmacol; 1987 Feb; 65(2):165-71. PubMed ID: 3567731.
    Abstract:
    This study was conducted because of the paucity of information concerning gender differences in the cardiovascular and metabolic responses to cold stress. Lightly clad men (n = 8) and women (n = 8) were tested in 21 and 5 degrees C environments during a 20-min rest, followed by 20 min each of 50, 100, and 150 W of exercise. At 21 degrees C there was no gender differences in VO2 or cardiac output. Cold lowered skin temperature more in women than in men, but women demonstrated no differences in heart rate, stroke volume, or VO2 at 5 and 21 degrees C. The women's noradrenaline levels in the cold were higher than comparable 21 degrees C data at rest and 50 W and increased with work intensity in both tests. In contrast, men had a lower heart rate, higher stroke volume, and higher VO2 throughout the 5 degrees C treatment compared with 21 degrees C. The men's noradrenaline response to 5 degrees C was similar to that of women at rest and 50 W, but the level subsequently declined at 100 and 150 W. Thus, the women do not show a heart rate-stroke volume shift in either resting or exercising states in cold environments. Furthermore, the data fail to support that either skin cooling or changes in noradrenaline cause the bradycardia and enhanced stroke volume seen in men.
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