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  • Title: Hepatic Epstein-Barr Virus-Associated Smooth Muscle Tumor in a Heart and Liver Transplant Recipient.
    Author: Johnson BM, Iskandar JP, Farha N, Yerian L, Modaresi Esfeh J, Lindenmeyer C.
    Journal: ACG Case Rep J; 2022 Jun; 9(6):e00782. PubMed ID: 35677812.
    Abstract:
    Epstein-Barr virus (EBV)-associated smooth muscle tumors (SMT) have been described in immunosuppressed states, including in post-transplant patients. Here, we discuss a heart-liver transplant recipient who was found to have multifocal hepatic EBV-SMT. His immunosuppression was initially transitioned from tacrolimus to sirolimus because of the proposed benefits of the mechanistic target of rapamycin inhibitors on EBV-SMT. Unfortunately, he suffered acute rejection of his liver allograft while on sirolimus therapy, which ultimately led to consideration of retransplantation.
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