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  • Title: [Insulin-forming activity of monolayer cultures of pancreatic islet cells from cattle fetuses].
    Author: Fedotov VP, Bliumkin VN, Babikova RA, Sadovnikova NV, Abramova VV.
    Journal: Biull Eksp Biol Med; 1978 Aug; 86(8):235-8. PubMed ID: 356913.
    Abstract:
    The radioimmunological method was applied to the study of insulin content in the growth medium of primary monolayer cultures of bovine fetal pancreatic islet cells grown with usual and increased (300 mg%) glucose content. The latter led to an enhanced insulin secretion. The results of cytological study demonstrated a definite interrelationship between the mitotic activity of culture cells and the intensity of insulin secretion into the medium.
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