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  • Title: Inactivation of sarin and soman by cyclodextrins in vitro.
    Author: Désiré B, Saint-André S.
    Journal: Experientia; 1987 Apr 15; 43(4):395-7. PubMed ID: 3569488.
    Abstract:
    Cyclodextrins catalyzed the inactivation of sarin and soman but did not inactivate tabun and VX. Furthermore, sarin and soman showed greater affinity for beta-cyclodextrin than for alpha- or gamma-cyclodextrins. Thus beta-cyclodextrin appears to be an attractive starting material for the preparation of a catalyst able to inactivate sarin and soman more effectively. Such a catalyst might contribute to improving the therapy of poisoning caused by these two nerve agents.
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