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  • Title: Tobacco-specific N-nitrosamines in dry snuff.
    Author: Adams JD, Owens-Tucciarone P, Hoffmann D.
    Journal: Food Chem Toxicol; 1987 Mar; 25(3):245-6. PubMed ID: 3570114.
    Abstract:
    Case-control studies have shown that the oral use of dry snuff has an aetiological association with cancer of the oral cavity. This communication reports high concentrations of the powerful carcinogen N'-nitrosonornicotine (9.37-55.3 micrograms/g), and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (1.98-14.4 micrograms/g) and of N'-nitrosoanatabine (18.8-40.2 micrograms/g) and N'-nitrosoanabasine (0.66-1.17 microgram/g) in three popular brands of dry snuff available in the USA.
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