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  • Title: Esophageal Melanocytosis: report of two cases and review of a rare and misunderstood entity.
    Author: Dubail A, Dano H, de Suray N, Hassaini H, Jouret-Mourin A.
    Journal: Acta Gastroenterol Belg; 2022; 85(2):390-392. PubMed ID: 35709783.
    Abstract:
    Esophageal melanocytosis (EM) is a rare entity, which is characterized by a non-atypical melanocytic proliferation and melanin deposits in the esophageal mucosa. The confusion between the terms of melanosis and melanocytosis in the literature, the rarity of this lesion (less than 50 cases reported in the literature), its uncertain pathobiological course and the lack of experience of pathologists and gastroenterologists prompt us to draw the attention to this particular entity by reporting two cases and reviewing the literature. Magnifying endoscopy to observe intensive melanin accumulation followed by a biopsy are key for the diagnosis.
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