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  • Title: Peroxisomal localization and activation by bivalent metal ions of ureidoglycolate lyase, the enzyme involved in urate degradation in Candida tropicalis.
    Author: Takada Y, Tsukiji N.
    Journal: J Bacteriol; 1987 May; 169(5):2284-6. PubMed ID: 3571167.
    Abstract:
    Ureiodoglycolate lyase (EC 4.3.2.3) was found only in the peroxisomes in urate-induced Candida tropicalis. The enzyme was markedly activated by the bivalent metal ions Mn2+, Fe2+, and Ni2+. The activation by Mn2+ was suggested to be the result of its binding to the apoenzyme.
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