These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Cardiac Tamponade as a Recurrence of Angioimmunoblastic T-Cell Lymphoma with the Detection of a p.Gly17Val RHOA Mutation in the Pericardial Effusion.
    Author: Tsuboi Y, Iimura Y, Matsumura F, Nanmoku T, Suma S, Matsuoka R, Nakagawa T, Nakagawa D, Suehara Y, Hattori K, Sato K, Maruyama Y, Sakamoto T, Yokoyama Y, Kato T, Kurita N, Nishikii H, Obara N, Ieda M, Chiba S, Sakata-Yanagimoto M.
    Journal: Intern Med; 2023 Feb 15; 62(4):595-600. PubMed ID: 35732446.
    Abstract:
    Angioimmunoblastic T-cell lymphoma (AITL) is an intractable type of T-cell lymphoma. We and others have identified that the p.Gly17Val RHOA mutation is specifically identified in AITL. We herein report a patient whose condition deteriorated, resulting from massive pericardial effusion one month after undergoing autologous transplantation for AITL. He was diagnosed with cardiac tamponade caused by AITL recurrence in the presence of the p.Gly17Val RHOA mutation as well as T-lineage cells with an aberrant immune-phenotype in the pericardial effusion. This case suggests that a precision medicine approach by detecting the presence of a p.Gly17Val RHOA mutation is useful for the management of AITL.
    [Abstract] [Full Text] [Related] [New Search]