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  • Title: [Unusual giant inclusions in blast cells during acute transformation of chronic myeloid leukemia. Cytochemical and ultrastructural study (author's transl)].
    Author: Lejeune F, Turpin F, Lortholary P.
    Journal: Pathol Biol (Paris); 1978 Jan; 26(1):7-11. PubMed ID: 358097.
    Abstract:
    Unusual giant inclusions are reported in the blast cells during the blastic crisis of a chronic granulocytic leukemia. These inclusions coudl have their origin in degenerated mitochondria, and acid phosphatase positivity suggests fusion with lysosomes. A possible viral etiology is discussed.
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