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  • Title: In vitro antibacterial activity of irloxacin (E-3432) on clinical isolates.
    Author: Coll R, Esteve M, Moros M, Xicota MA, Parés J.
    Journal: Drugs Exp Clin Res; 1987; 13(2):75-7. PubMed ID: 3582134.
    Abstract:
    Irloxacin (E-3432) is a new quinolone derivative. In this study, the activity of irloxacin was compared with that of nalidixic acid, norfloxacin and ciprofloxacin against strains of clinical isolates. Irloxacin showed greater in vitro activity than nalidixic acid, similar activity to norfloxacin and lower activity than ciprofloxacin. Against Staphylococcus, the MIC range of E-3432 was 0.06-1 mg/l, better than the other compounds studied.
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