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  • Title: [Action of the anti-inflammatory agent Lonazolac on experimentally-induced acute inflammation of human skin].
    Author: Dethlefs J.
    Journal: Z Rheumatol; 1978; 37(7-8):254-9. PubMed ID: 358658.
    Abstract:
    Using two experimental models of acute dermatitis in man, Lonazolac proved to possess dose-dependent anti-inflammatory effects. No untoward side effects were seen even at the higher doses of the drug. The results are consistent with animal studies: In its effect on the acute experimental dermatitis, Lonazolac resembles indomethacin more closely than oxyphenbutazone. It is superior to the comparable anti-inflammatory drugs in its effect on the inflammatory erythema of the skin; in its effect on the inflammatory edema of the skin, it stands between oxyphenbutazone and indomethacin.
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