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  • Title: [Changes in central hemodynamics in chronic liver diseases (radiocardiologic study)].
    Author: Loginov AS, Khodarev NN, Astaf'eva OV, Sakharova GN.
    Journal: Med Radiol (Mosk); 1987 Apr; 32(4):26-30. PubMed ID: 3586907.
    Abstract:
    Some indices of central hemodynamics: cardiac and systolic indices, specific peripheral resistance and circulating plasma and blood volumes were studied in 136 patients with chronic liver diseases using radionuclide cardiography. I. Three hemodynamic types of blood circulation (hyper-, eu- and hypokinetic) were defined in patients with chronic liver diseases as well as in healthy persons. II. In liver cirrhosis and ascites the number of patients with the hyperkinetic type of circulation increased significantly, mainly at the expense of patients with hypervolemia. III. A significant decrease in circulating plasma and blood volumes was noted in patients with liver cirrhosis complicated by ascites, with the hypokinetic type of circulation. It should be borne in mind in administration of diuretics to such patients. The above results suggested that different types of circulation in patients with chronic liver diseases were formed under the influence of the disease against a background of existing constitutionally and genetically determined hemodynamic heterogeneity.
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