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  • Title: Non-ocular cancer in hereditary retinoblastoma survivors and relatives.
    Author: Derkinderen DJ, Koten JW, Wolterbeek R, Beemer FA, Tan KE, Den Otter W.
    Journal: Ophthalmic Paediatr Genet; 1987 Mar; 8(1):23-5. PubMed ID: 3587888.
    Abstract:
    An epidemiological survey has been carried out to establish the incidence of second malignant neoplasms in hereditary retinoblastoma survivors in The Netherlands and the relative risk of cancer in non-affected relatives. The cumulative incidence of second neoplasms was 19% at the age of 35 years. Fathers, unaffected by retinoblastoma, were at risk for pancreatic cancer, the relative risk being 8.3.
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