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  • Title: Numerical investigation of different viscosity models on pulsatile blood flow of thoracic aortic aneurysm (TAA) in a patient-specific model.
    Author: Faraji A, Sahebi M, SalavatiDezfouli S.
    Journal: Comput Methods Biomech Biomed Engin; 2023 Jun; 26(8):986-998. PubMed ID: 35882063.
    Abstract:
    Aortic aneurysm is one of the most common aortic diseases that can lead to unfortunate consequences. Numerical simulations have an important role in the prediction of the aftereffects of vascular diseases including aneurysm. In this research, numerical simulation of pulsatile blood flow is performed for a 3-dimensional patient-specific model of a thoracic aortic aneurysm (TAA). Since the choice of blood viscosity model may have a significant impact on the simulation results, the effects of four non-Newtonian models of blood viscosity namely Carreau, Casson, Herschel-Bulkley, power low, and the Newtonian model on the wall shear stress (WSS) distribution, shear rate, and oscillatory shear index (OSI) have been analyzed. Simulation results showed that all the non-Newtonian and Newtonian models generally, predict similar patterns for blood flow and shear rate. At high flow rates in the cardiac cycle, the WSS value for all the models are similar to each other except for the power-law model due to the shear thinning behavior. All models predict high values of OSI on the inner wall of the ascending aorta and broad areas of the inner wall of the aneurysm sac. However, the Newtonian model predicts the OSI less than the non-Newtonian models in some areas of the aneurysm sac. Results indicated that the Newtonian model generally can predict the hemodynamic parameters of the blood flow similar to the non-Newtonian but for more precise analysis and to predict the regions prone to rupture and atherosclerosis, choosing a proper non-Newtonian model is recommended.
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