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  • Title: [The influence of ritodrine-hcl (prepar), bunitrolol (stresson) and oxytocin (syntocinon) on Uteroplacental perfusion (author's transl)].
    Author: Leodolter S, Müller-Tyl E, Philipp K, Salem G, Janisch H.
    Journal: Z Geburtshilfe Perinatol; 1979 Apr; 183(2):111-7. PubMed ID: 35885.
    Abstract:
    The administration of betamimetics has proved to be useful for symptom-oriented treatment in patients with reduced utero-placental flow. In order to quantify the betamimetic effect flow measurements were carried out in a total of 12 sheep, yielding the following experimental results: 1) Betamimetics, up to a certain point which correlates with maternal heart rate, raise the uteroplacental flow-rate. 2) The use of cardio-selective betablocker prevents undesired betamimetic side-effects but there is also a loss of the rise in utero-placental flow rate. 3) In sheep pretreated with Oxytoxin the application of betamimetics not only offsets oxytoxin-action but also greatly improves utero-placental blood flow.
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