These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effect of methotrexate and actinomycin D on the frequency and ratio of early mitotic cells].
    Author: Vaniurikhina EA, Kuleshov NP.
    Journal: Tsitol Genet; 1987; 21(2):115-8. PubMed ID: 3590308.
    Abstract:
    Different methods for obtaining early mitotic chromosomes have been comparatively analyzed. Lymphocyte cultures have been treated with methotrexate, actinomycin-D and with a combination of both agents. It is shown that a high rate of chromosomes in prophase, prometaphase and mid-metaphase can be achieved by the combined methotrexate and actinomycin-D treatment of the lymphocyte culture. Methotrexate treatment of cultures is preferable to obtain the great number of early metaphase chromosomes.
    [Abstract] [Full Text] [Related] [New Search]