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  • Title: Needle biopsy of the pleura in the diagnosis of pleural effusion.
    Author: McAleer JJ, Murphy GJ, Quinn RJ.
    Journal: Ulster Med J; 1987 Apr; 56(1):54-7. PubMed ID: 3590388.
    Abstract:
    Needle biopsy of the parietal pleura was undertaken in 64 patients with undiagnosed pleural effusion. An adequate specimen was obtained in 96% of procedures. This was diagnostic in 45% of those due to malignancy and in 50% of those due to tuberculosis. A second biopsy improved the combined diagnostic yield in these two diseases from 32% to 46%. Pleural fluid cytology was unhelpful in establishing the presence of a malignancy, and culture of the biopsy specimen was helpful in one case.
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