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  • Title: [Lectin receptors in transitional cell tumors of the bladder].
    Author: Dmitruk IM, Zerbino DD, Lutsik AD.
    Journal: Vopr Onkol; 1987; 33(4):60-5. PubMed ID: 3590660.
    Abstract:
    Binding sites for lectins of peanuts, soya-beans and concanavalin A were identified in the tissues of normal human urinary bladder and its transitional cell tumors (31 patients) using the lectin-peroxidase technique. No binding sites for any of the lectins were found in normal urothelium. Receptors for peanut and soya-bean lectins were observed on the plasma membranes of 20% of tumor cells in transitional cell papillomas. A diffuse distribution of those lectins in tumor cell cytoplasm was interpreted as a tendency to malignant transformation of tumor. There were no concanavalin A receptors in tumor cells.
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