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  • Title: An unusual variant of membranous nephropathy with abundant crescent formation and recurrence in the transplanted kidney.
    Author: Hill GS, Robertson J, Grossman R, Perloff L, Barker CF.
    Journal: Clin Nephrol; 1978 Sep; 10(3):114-20. PubMed ID: 359208.
    Abstract:
    A patient with what initially appeared to be a typical membranous nephropathy had a progressive course to renal failure, nephrectomy, and transplantation. The nephrectomy specimen revealed abundant glomerular crescents and capsular synechiae. Post-transplantation the patient again developed a membranous nephropathy with florid crescents. Radioimmunoassay and indirect immunofluorescence tests failed to reveal anti-glomerular basement membrane antibody in the serum or kidney. It appears that there is a form of membranous nephropathy with crescent formation, unrelated to anti-GBM antibody, which has the capacity to recur after transplantation.
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