These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Photocatalytic Defluorinative Three-Component Reaction of α-Trifluoromethyl Alkenes, Alkenes, and Sodium Sulfinates: Synthesis of Monofluorocyclopentenes.
    Author: Li W, Chen X, Zhou L.
    Journal: Org Lett; 2022 Aug 19; 24(32):5946-5950. PubMed ID: 35926080.
    Abstract:
    A photocatalytic three-component reaction of α-trifluoromethyl alkenes, electron-rich alkenes, and sodium sulfinates for the synthesis of gem-difluoroalkenes in a radical/polar crossover manner was developed. Due to the strong electron-withdrawing nature of the sulfonyl group, the resultant gem-difluoroalkenes can be converted into various monofluorocyclopentenes via intramolecular base-mediated SNV reactions in one pot.
    [Abstract] [Full Text] [Related] [New Search]