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  • Title: [Morphometric ultrastructural study of the adreno- and noradrenocytes of the rat adrenal during immobilization stress of varying duration].
    Author: Arefolov VA, Malikova LA, Val'dman AV.
    Journal: Biull Eksp Biol Med; 1987 Jun; 103(6):743-6. PubMed ID: 3593961.
    Abstract:
    The ultrastructural organization of secretory granules, containing adrenaline (A) or noradrenaline (NA) was studied in chromaffin cells of the rat adrenal gland after 3-, 24- and 48-hour immobilization stress. Using cytochemical electron microscopic Tranzer's method and the method of morphometry, the number of normal dense cores, "empty" and "semiempty" vesicles was calculated. It was shown that the total content of vesicles and the ratio of investigated types of both adrenaline- and noradrenaline-accumulating granules were markedly changed during stress. The degree of such stress-induced reorganization depended on the stage of stress reaction and involved first A-cells and then NA-cells.
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