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  • Title: Atogepant for migraine.
    Author: Bedrin K, Ailani J.
    Journal: Drugs Today (Barc); 2022 Aug; 58(8):399-405. PubMed ID: 35983926.
    Abstract:
    Atogepant is a selective oral, small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist that has been approved for preventive treatment of migraine. CGRP is a neuropeptide involved in vasodilation and cerebrovascular regulation. CGRP is the most potent vasoactive constituent of the cerebrovascular trigeminal neuronal system and has a key role in migraine. Medications targeting CGRP are being used as migraine preventive and abortive treatments.
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