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  • Title: Surgery for acromegaly: Indications and goals.
    Author: Bray DP, Mannam S, Rindler RS, Quillin JW, Oyesiku NM.
    Journal: Front Endocrinol (Lausanne); 2022; 13():924589. PubMed ID: 35992136.
    Abstract:
    Acromegaly is a disease that occurs secondary to high levels of GH, most often from a hormone-secreting pituitary adenoma, with multisystem adverse effects. Diagnosis includes serum GH and IGF-1 levels, and obtaining an MRI pituitary protocol to assess for a functional pituitary adenoma. Attempted gross total resection of the GH-secreting adenoma is the gold standard in treatment for patients with acromegaly for a goal of biochemical remission. Medical and radiation therapies are available when patients do not achieve biochemical cure after surgical therapy.
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