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  • Title: Gamma variate analysis of pulmonary dilution curves for quantitation of left-to-right cardiac shunts.
    Author: Olkkonen H.
    Journal: Nuklearmedizin; 1978 Jul; 17(3):103-5. PubMed ID: 360172.
    Abstract:
    Left-to-right shunts were quantified in patients with atrial septal defect using a gamma variate least square fit to radionuclide pulmonary dilution curves. All patients were studied with cardiac catheterization. There was a close correlation between the Fp/Fs ratios obtained by oximetry in cardiac catheterization and by gamma variate analysis. The results suggest that the radionuclide dilution method is sufficiently reliable to be used as a screening tests for the detection and quantitation of left-to-right cardiac shunts.
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