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  • Title: Epithelioid Hemangioma of Bone: A Rare Vascular Neoplasm. A Case Report and Literature Review.
    Author: Savvidou O, Korkolopoulou P, Lakiotaki E, Sioutis S, Vottis C, Gavriil P, Melissaridou D, Papagelopoulos P.
    Journal: J Long Term Eff Med Implants; 2022; 32(4):47-55. PubMed ID: 36017927.
    Abstract:
    Epithelioid hemangioma (EH) of bone is a rare benign, albeit locally aggressive vascular neoplasm. It is usually solitary and involves the metaphysis or diaphysis of long tubular bones, especially in the lower extremities. Rarely it may present as multifocal lesions. The differential diagnosis includes malignant vascular bone tumors such as epithelioid hemangioendothelioma and epithelioid angiosarcoma. Clinical presentation and radiographic and histological findings are not specific and diagnosis is based mostly on immunohistochemical and molecular studies. There is no consensus regarding the optimal treatment. Curettage and bone grafting or en bloc resection are the current treatment options, however local recurrence have been reported. We present a case of multifocal EH of the distal tibia, distal fibula and hindfoot in a 38 year-old male managed with curettage, radiofrequency ablation and cement osteoplasty. The imaging features, histological findings and treatment options of this rare vascular tumor are discussed.
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