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  • Title: Systemic autonomic neuropathy in open-angle glaucoma.
    Author: Clark CV, Mapstone R.
    Journal: Doc Ophthalmol; 1986; 64(2):179-85. PubMed ID: 3608758.
    Abstract:
    Systemic autonomic nerve function was assessed in 67 patients with open-angle glaucoma and 76 age- and sex-matched control subjects, using a series of well-established tests based upon cardiovascular reflex responses to standardised stimuli. Parasympathetic neuropathy was present in 37.3% of open-angle glaucoma patients compared with 2.6% of the control group. Demonstration of a significant association between autonomic neuropathy and primary glaucoma may provide a logical rationale for the efficacy of autonomic medication in glaucoma therapeutics; the prognostic implications are discussed.
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