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  • Title: Evaluation of fenbendazole for larvacidal effect in experimentally induced Parascaris equorum infections in pony foals.
    Author: Vandermyde CR, DiPietro JA, Todd KS, Lock TF.
    Journal: J Am Vet Med Assoc; 1987 Jun 15; 190(12):1548-9. PubMed ID: 3610763.
    Abstract:
    Fifteen pony foals were inoculated with 1,500 +/- 298.7 infective Parascaris equorum eggs. The foals were assigned to 3 treatment groups. Treatments included 10 mg of fenbendazole/kg given once on postinoculation day (PID) 11, 10 mg of fenbendazole/kg given daily on PID 11 to 15, and no treatment (controls). The foals were euthanatized on PID 25 and examined for P equorum larvae in the small intestine, lungs, and liver. Significantly (P less than 0.05) lower mean numbers of P equorum larvae were found in the small intestine of foals treated on PID 11 to 15 (1.4 [range, 0 to 6]) than in the small intestine of foals treated on PID 11 (428.2 [range, 0 to 777]) and in controls (500 [range, 284 to 802]).
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