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  • Title: Coexistence of papillary and nodular carcinomas in the urinary bladder.
    Author: Kakizoe T, Matsumoto K, Tobisu K, Takai K, Teshima S, Kishi K.
    Journal: Jpn J Clin Oncol; 1987 Jun; 17(2):179-86. PubMed ID: 3613141.
    Abstract:
    Of 203 patients with transitional cell carcinoma of the urinary bladder which had been cystectomized and examined by step-sectioning during the period between 1969 and 1986, 33 had coexistent papillary, papillonodular and/or nodular carcinomas in the bladder. Of them, 12 (36%) had a history of papillary carcinomas, 26 (79%) had multiple tumors and 22 (67%) had a concomitant carcinoma in situ, and/or mucosal dysplasia. Moreover, microscopic papillary structures were identified in 32 out of the 33 (97%) cases with papillonodular and/or nodular carcinomas, indicating some of the nodular invasive carcinomas in the bladder to have developed from papillary carcinomas.
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