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  • Title: [Features of changes in blood pressure and blood flow in the common carotid artery of monkeys exposed aboard the biosatellite Cosmos-1514].
    Author: Krotov VP, Sandler G, Badakva AM, Khaĭnz D, Magedov VS.
    Journal: Kosm Biol Aviakosm Med; 1987; 21(3):69-74. PubMed ID: 3613499.
    Abstract:
    Preflight the rhesus-monkey Bion was implanted with sensors and transducers to measure blood pressure and linear flow velocity in the common carotid artery and to compare these parameters with central circulation. At the early flight stage blood pressure increased, blood flow decreased and resistance in the area grew. The last change can be regarded as a compensatory reaction that can provide rapid adaptation of regional circulation to changes in systemic circulation. At later flight stages blood pressure showed distinct circadian oscillations and blood flow, a significant increase when compared to the ground-based 36-hour control study. Regulatory mechanisms of the cardiovascular system changed to the greatest extent on flight day 2. This manifested as a decrease of the amplitude of circadian oscillations of the above circulation parameters. Signs of cardiovascular adaptation to the effects of microgravity were discerned on flight days 3 to 5.
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