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  • Title: Adenoid Ameloblastoma Versus Dentinogenic Ghost Cell Tumor.
    Author: Bastos VC, Gomes CC, Gomez RS.
    Journal: Head Neck Pathol; 2023 Mar; 17(1):275-276. PubMed ID: 36169792.
    Abstract:
    BACKGROUND: A recent systematic review published in Head and Neck Pathology found that 3.8% of dentinogenic ghost cell tumors harbor duct-like/ cribriform architecture. Herein we discuss this finding regarding the differential diagnosis of this tumor with adenoid ameloblastoma. METHODS: A critical review of some microscopic findings reported in a recent paper published in the Head and Neck Pathology Journal was done. RESULTS: Although there are overlapping microscopic features with dentinogenic ghost cell tumor, adenoid ameloblastoma is distinguished by the combination of duct-like structures and whorls/morules. In our opinion, at least some cases previously diagnosed as dentinogenic ghost cell tumors may now be more accurately classified as adenoid ameloblastoma. CONCLUSION: We conclude that a reassessment of dentinogenic ghost cell tumor cases using the diagnostic criteria proposed by the new WHO classification of Head and Neck Tumors (2022) is warranted.
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