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  • Title: Segregation of α- and β-Globin Gene Cluster in Vertebrate Evolution: Chance or Necessity?
    Author: Iarovaia OV, Ulianov SV, Ioudinkova ES, Razin SV.
    Journal: Biochemistry (Mosc); 2022 Sep; 87(9):1035-1049. PubMed ID: 36180994.
    Abstract:
    The review is devoted to the patterns of evolution of α- and β-globin gene domains. A hypothesis is presented according to which segregation of the ancestral cluster of α/β-globin genes in Amniota occurred due to the performance by α-globins and β-globins of non-canonical functions not related to oxygen transport.
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