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  • Title: [Effect of adaptation to physical loading on the adrenoreactivity of the isolated rat atrium].
    Author: Chinkin AS, Shimkovich MV.
    Journal: Biull Eksp Biol Med; 1987 Jul; 104(7):23-6. PubMed ID: 3620641.
    Abstract:
    The experiments on the isolated atria of rats, previously adapted to swimming exercises, have established a significant decrease in the heart rate and an increase in positive inotropic effect of noradrenaline (4 X 10(-7) and 6 X 10(-7) M). After beta-adrenoceptor blockade with propranolol (2 X 10(-6) M) the inotropic effect of an alpha-adrenoceptor agonist mezaton on the isolated atrium of the adapted rats was greater than in nonadapted controls.
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