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  • Title: [Cells that maintain long-term hematopoiesis in culture do not possess the capacity for regeneration following irradiation].
    Author: Deriugina EI, Drize NI, Chertkov IL.
    Journal: Biull Eksp Biol Med; 1987 Jul; 104(7):96-9. PubMed ID: 3620659.
    Abstract:
    It has been revealed by competitive repopulation assay that hemopoietic stem cells capable of supporting long-term hemopoiesis in the culture failed to regenerate after irradiation. 19 weeks after irradiation with 4 Gy the content of hemopoietic stem cells was 0.5% normal, while regeneration of CFUs was achieved up to subnormal level.
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