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  • Title: [State of the antioxidant system during corazole kindling in rats].
    Author: Tupeev IR, Bordiukov MM, Kryzhanovskiĭ GN, Nikushkin EV.
    Journal: Biull Eksp Biol Med; 1987 Aug; 104(8):167-9. PubMed ID: 3620672.
    Abstract:
    Antioxidation system was investigated in rats during kindling formation caused by daily administration of corazole in under-threshold doses. No changes have been observed in the activity of superoxide dismutase, glutathione peroxidase, glutathione reductase and alpha-tocopherol content in the rat brain and blood. It is suggested that corazole-induced predisposition to epileptic activity is formed by mechanisms which are not associated with lipid metabolism in nervous tissue.
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