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  • Title: Lack of evidence that the XqYq pairing tips at meiosis in the mouse show hypersensitivity to DNAse I.
    Author: Separovic ER, Chandley AC.
    Journal: Chromosoma; 1987; 95(4):290-4. PubMed ID: 3622083.
    Abstract:
    In situ nick translation procedures have been applied to meiotic metaphase I divisions of the normal and XY, Sxr mouse. Unlike in man, where the pairing tips of the XY bivalent show a special sensitivity to DNAse I nicking, no such sensitivity can be detected for either of these types of mouse. Hypersensitivity in the D-band equivalent region of the X chromosome does, however, exist, this site being early replicating in somatic cells and housing the X inactivation centre (Xce).
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