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  • Title: [Torre-Muir syndrome. Sebaceous gland tumors indicate colon carcinoma and other internal malignant tumors].
    Author: Karsten U, Christophers E, Sterry W.
    Journal: Dtsch Med Wochenschr; 1987 Aug 21; 112(34):1296-301. PubMed ID: 3622267.
    Abstract:
    The Torre-Muir syndrome belongs to a group of hereditory cancers and expresses itself in the occurrence of cutaneous gland tumors and (often multiple) carcinoma of the colon. The syndrome is probably a phenotypical manifestation of the "cancer family" syndrome, in which familial carcinoma of the colon also occurs. A case of Torre-Muir syndrome in a 43-year-old man is described. Because of the dermatological features, the colon carcinoma was diagnosed in time. Family investigations revealed another case of complete Torre-Muir syndrome, as well as a remarkable frequency of colon carcinoma in one family branch. Inheritance is autosomal dominant. The characteristic morphological features of the sebaceous gland neoplasias makes an early, often life-saving, diagnosis possible.
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