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  • Title: Pyrroxamycin, a new antibiotic taxonomy, fermentation, isolation, structure determination and biological properties.
    Author: Yano K, Oono J, Mogi K, Asaoka T, Nakashima T.
    Journal: J Antibiot (Tokyo); 1987 Jul; 40(7):961-9. PubMed ID: 3624075.
    Abstract:
    A strain of streptomycete was found to produce a new antibiotic pyrroxamycin. This compound was isolated from the culture broth of Streptomyces sp. S46506. The chemical structure was determined to be 4,5-dichloro-2-(6',8'-dichloro-4'H-1',3'-benzodioxin-4'-yl)-3-nitr opyrrole by its chemical character and 1H and 13C NMR spectral analysis. Pyrroxamycin was active against Gram-positive bacteria and dermatophytes.
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