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  • Title: Flexible acoustic lens-based surface acoustic wave device for manipulation and directional transport of micro-particles.
    Author: Huang J, Ren X, Zhou Q, Zhou J, Xu Z.
    Journal: Ultrasonics; 2023 Feb; 128():106865. PubMed ID: 36260963.
    Abstract:
    Microfluidics is an emerging technology that is playing increasingly important roles in biomedical and pharmaceutical research and development. Surface acoustic waves (SAWs) have been combined with microfluidics technology to establish a SAW-based microfluidics technology that uses the unique interaction between the two techniques to manipulate substances effectively in fluids on the surface of a substrate. This paper reports a method to generate SAWs using conventional planar ultrasonic transducers and acoustic lenses. Additionally, this method is introduced to manipulate particles effectively on a substrate surface. It is demonstrated that the particle positions can be manipulated precisely in any direction on the substrate surface, thus enabling high-precision particle manipulation. We also proposed the generation of nonplanar SAWs via appropriate design of the acoustic lens and realized directional particle transport. In addition, structures to enhance forward-propagating acoustic beams are proposed. The proposed method has potential for use in microfluidics and biomedical applications, allowing tasks such as flexible cell manipulation on a chip to be performed without complex design or micromachining.
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