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  • Title: [Mitral valve dysplasia as a cardiac surgery problem (a clinico-morphological comparison)].
    Author: Konstantinov BA, Alekseeva LA, Kulagina TI, Kuznetsova LM, Sheremet'eva GF.
    Journal: Kardiologiia; 1987 Jun; 27(6):19-23. PubMed ID: 3626273.
    Abstract:
    Clinical appearance of mitral incompetence associated with mitral dysplasia (abnormal connective tissue structure in the cusps and chordae, with significant accumulation of acid mucopolysaccharides) is dependent on the extent of regurgitation, its pathogenetic mechanism (sudden or progressive), the presence of the prolapsing cusp syndrome, and attendant complications (endocarditis, chord abruption). Indications for surgery were marked regurgitation in 94% of patients, and septic endocarditis in 6%.
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