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  • Title: Urinary trace amine excretion and platelet monoamine oxidase activity in schizophrenia.
    Author: Yoshimoto S, Kaku H, Shimogawa S, Watanabe A, Nakagawara M, Takahashi R.
    Journal: Psychiatry Res; 1987 Jul; 21(3):229-36. PubMed ID: 3628609.
    Abstract:
    The relationship between subtypes of schizophrenia classified by ICD-9 and 24-hour urinary beta-phenylethylamine (PEA) and phenylacetic acid (PAA) excretion has been studied. Schizophrenia was divided into two types: paranoid and nonparanoid. Increased urinary PEA excretion was found in paranoid schizophrenics, but urinary PAA excretion did not show any significant difference between schizophrenics and normal subjects. A relationship between platelet monoamine oxidase (MAO) activity and urinary PEA excretion was found. These findings offer some indication that PEA may play a role in the pathogenesis of schizophrenia.
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