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  • Title: Urinary C-peptide excretion at onset of insulin dependent diabetes mellitus in children.
    Author: Ivarsson SA, Johansson E, Nilsson KO, Thorell JI.
    Journal: Acta Paediatr Scand; 1987 Jul; 76(4):608-11. PubMed ID: 3630678.
    Abstract:
    The 24-hour urinary excretion of C-peptide and the plasma C-peptide concentration were measured at the onset of insulin dependent diabetes mellitus (IDDM) in children. The excretion of C-peptide was twice as high as that found in normal control subjects, whereas the plasma C-peptide values were markedly lower, indicating increased urinary leakage of C-peptide in this phase of the disease. In the diabetic children under seven years of age the mean value of C-peptide excretion was clearly lower than in the older children.
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